Antigen-presenting cells and the eye by Manfred Zierhut, Hans-Georg Rammensee, Wayne Streilein

By Manfred Zierhut, Hans-Georg Rammensee, Wayne Streilein

Lately the significance of antigen-presenting cells and their impression at the eyes has been elucidated. we now have realized that just about each constitution of the attention harbors those cells, but they vary of their actions and hence within the ways that they safeguard opposed to - or perform - ailments of the attention. Antigen-Presenting Cells and the attention summarizes present wisdom approximately ACPs typically, and their function within the eye, particularly.

Show description

Read Online or Download Antigen-presenting cells and the eye PDF

Best ophthalmology books

Eye Pathology: An Illustrated Guide

This ebook is a entire, in-depth, and up to date source on eye pathology that might be of serious useful price for ophthalmic and common pathologists and ophthalmologists. Congenital abnormalities, inflammatory stipulations, infections, accidents, degenerative ailments, and tumors are all coated by means of greater than seven-hundred photographs.

2007-2008 Basic and Clinical Science Course Section 11: Lens and Cataract

Stories the anatomy, body structure, embryology, and pathology of the lens. additionally offers an summary of lens and cataract surgical procedure, and describes the problems of surgical procedure.

Ophthalmology Secrets in Color

This thoroughly up to date top-seller brings you crucial ophthalmology assistance within the basic, question-and-answer structure of the hugely well known secrets and techniques Series®. From easy technological know-how to visible fields and refraction, from the fundamental eye examination to discussions of all ophthalmologic problems, from touch lenses to corneal transplantation, difficulties of the getting older eye, and pediatric disorders-this booklet provides all of the key components of ophthalmology for medical use, rounds, and board instruction.

Image Analysis and Modeling in Ophthalmology

Electronic fundus photos can successfully diagnose glaucoma and diabetes retinopathy, whereas infrared imaging can convey alterations within the vascular tissues. Likening the attention to the normal digital camera, snapshot research and Modeling in Ophthalmology explores the applying of complicated photo processing in ocular imaging.

Extra resources for Antigen-presenting cells and the eye

Sample text

J Exp Med 1974; 139:1431–1445. Leenen PJ, Radosevic K, Voerman JS, et al. Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover. J Immunol 1998; 160:2166–2173. Kamath AT, Pooley J, O’Keeffe MA, et al. The development, maturation, and turnover rate of mouse spleen dendritic cell populations. J Immunol 2000; 165: 6762–6770. Mishima Y. Melanosomes in phagocytic vacuoles in Langerhans cells. Electron microscopy of keratin-stripped human epidermis.

24 Stein-Streilein 20. Streilein JW. New insights into immunologic tolerance. Peripheral tolerance induction: lessons from immune privileged sites and tissues. Transplant Proc 1996; 28: 2066–2070. Streilein JW. Ocular immune privilege: therapeutic opportunities from an experiment of nature. Nat Rev Immunol 2003; 3:878–889. Chen Y, Inobe J, Weiner HL. Induction of oral tolerance to myelin basic protein in CD8-depleted mice: both CD4+ and CD8+ cells mediate active suppression. J Immunol 1995; 155:910–916.

The F4/80+ cell secretes IL-10 and TGFß. The MIP-2 recruits NKT cells to the same region of the spleen. The TCR on the NKT cell binds to CD1d on the F4/80 cell and the MZ B cell (dark green). The interaction of the NKT cell with CD1d on the APC induces the production of RANTES that recruits more F4/80 APC and CD8+ T cells to the region. The NKT cell also produces immunosuppressive cytokines, IL-10 and TGFß. Both the F4/80+ APC and the MZ B cell are capable of presenting the antigen (OVA) to the T cells in the cell cluster.

Download PDF sample

Rated 4.96 of 5 – based on 26 votes